Anticancer Potency of Dimethyl 2-(2-Hydroxy-2-Methoxypropilidine) Malonate in Kombucha

Authors

  • Opik Taupiqurrohman Department of Biology Faculty of Science and Technology UIN Sunan Gunung Djati Bandung, Indonesia
  • Firman Rezaldi Program Studi Farmasi, Fakultas Sains Farmasi Kesehatan, Universitas Mathla'ul Anwar Banten
  • Dina Amalia Department of Biology Faculty of Science and Technology UIN Sunan Gunung Djati Bandung
  • Yani Suryani Department of Biology Faculty of Science and Technology UIN Sunan Gunung Djati Bandung

DOI:

https://doi.org/10.15575/biodjati.v7i1.14634

Keywords:

dimethyl 2- (2-Hydroxy-2-Methoxypropilidine) malonate, EGFR, in silico, Kombucha

Abstract

Kombucha has an anticancer potency because it has dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate compound. The research aimed to verify the compound dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate as an anticancer with the in-silico method, namely the molecular docking approach, drug likeness profile, and ADMET test. The tools used were the PyRx, Discovery Studio Visualizer, Sanjeevini, and pkCSM. The research material consisted of 3D Dimethyl 2-(2-Hydroxy-2-Methoxypropilidine) Malonate and Epidermal Growth Factor Receptor (EGFR). The analysis showed Dimethyl 2-(2-Hydroxy-2-Methoxypropilidine) Malonate is safe for consumption and can suppress cancer cells. 

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Published

30-05-2022

How to Cite

Taupiqurrohman, O., Rezaldi, F., Amalia, D., & Suryani, Y. (2022). Anticancer Potency of Dimethyl 2-(2-Hydroxy-2-Methoxypropilidine) Malonate in Kombucha. Jurnal Biodjati, 7(1), 86–94. https://doi.org/10.15575/biodjati.v7i1.14634

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Vol. 7 No. 1 (2022): May

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